Abstract #4485

Movement Abnormalities in the Left Ventricle of Thalassemia Major Patients

Antonella Meloni¹, Vincenzo Positano¹, Pier Paolo Bitti², Antonella Carollo³, Letizia Gulino¹, Antonino Vallone⁴, Chiara Tudisca⁵, Elisabetta Chiodi⁶, Massimo Lombardi¹, Alessia Pepe¹

¹CMR Unit, Fondazione G. Monasterio CNR-Regione Toscana and Institute of Clinical Physiology, Pisa, Italy; ²Servizio Immunoematologia e Medicina Trasfusionale, O. San Francesco, Nuoro, Italy; ³Servizio Talassemia-U.O. Pediatria Talassemia, Az. Osp. "Sant'Antonio abate", Trapani, Italy; ⁴Istituto di Radiologia Az. Osp. "Garibaldi", Presidio Ospedaliero Nesima, Catania, Italy; ⁵Istituto di Radiologia, Policlinico "Paolo Giaccone", Palermo, Italy; ⁶Servizio Radiologia Ospedaliera-Universitaria, Arcispedale S. Anna di Ferrara, Ferrara, Italy

Movement abnormalities in the left ventricle (LV) are not really frequent in thalassemia major patients (6%) and are predominant in the medium anterior, anterolateral and septal segments. Movement abnormalities are associated with age, myocardial iron overload, LV dilation and dysfunction and myocardial fibrosis.