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Abstract #4489

Assessing Cardiac Kinetics Using Highly Accelerated Free Breathing 2D Through-Time Radial GRAPPA Compared to Cartesian Real-Time and Segmented Cine Imaging

Jeremy D. Collins1, Bruce S. Spottiswoode2, Haris Saybasili3, Mark A. Griswold3, 4, Nicole Seiberlich3, L. Cort Sommerville5, Keyur Parekh1, Michael Markl6, 7, James C. Carr5

1Radiology, Northwestern University, Chicago, IL, United States; 2Cardiovascular MR R&D, Siemens Healthcare, Chicago, IL, United States; 3Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States; 4Radiology, Case Western Reserve University, Cleveland, OH, United States; 5Radiology, Northwestern University, Chicago, Il, United States; 6Radiology, Northwestern University, Chiago, IL, United States; 7Biomedical Engineering, Northwestern University, Chicago, IL, United States

This pilot study evaluates the clinical feasibility of highly accelerated radial GRAPPA real-time bSSFP acquisitions for left ventricular diastology, comparing to accelerated Cartesian real-time and segmented bSSFP acquisitions. Real-time GRAPPA acquisitions with effective temporal resolutions as low as 25 msec were clinically feasible, with adequate image quality to identify the blood pool-myocardial boundary with clear separation of diastolic filling phases. Image quality was limited for trabecular assessment, however. The real-time GRAPPA acquisitions were more accurate for diastolic assessment than Cartesian real-time or Cartesian segmented acquisitions compared to echocardiography. Work is ongoing to assess beat-to-beat quantitative differences in left ventricular diastology.