Matthias Alexander Dieringer1, 2, Marcel Prothmann2, Florian von Knobelsdorff-Brenkenhoff1, 2, Andreas Greiser3, Christina Eichhorn, Thoralf Niendorf1, 4, Jeanette Schulz-Menger1, 2
1Berlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrueck Center for Molecular Medicine, Berlin, Germany; 2Working Group on Cardiovascular Magnetic Resonance, Experimental and Clinical Research Center (ECRC), Berlin, Germany; 3Siemens AG, Erlangen, Germany; 4Experimental and Clinical Research Center (ECRC), a cooperation of the Charit Medical Faculty and the Max-Delbrueck Center for Molecular Medicine, Berlin, Germany
Cardiovascular MR (CMR) offers the unique capability for non-invasive characterization and differentiation of myocardial tissue. Viability imaging including detection of myocardial infarction is usually based on late Gadolinium enhanced (LGE) imaging. To deliver more precise information about pathogenesis and classification of cardiac disorders, quantitative MR imaging is promising to characterize stage and progress of complex pathophysiological processes. We propose a method that combines quantitative T1 and semi quantitative perfusion imaging to enable intra-individual assessment of impact and progress of cardiac diseases on myocardial tissue viability. The technique is presented on two patients with chronic myocardial infarction.