Abstract #4525

In Vivo Performance of Myocardial Background Suppression

Terrence Jao¹, Hung Phi Do², Krishna S. Nayak³

¹Biomedical Engineering, University of Southern California, Los Angeles, CA, United States; ²Department of Physics, University of Southern California, Los Angeles, CA, United States; ³Electrical Engineering, University of Southern California, Los Angeles, CA, United States

Myocardial arterial spin labeling (ASL) is a technique for measuring myocardial perfusion and perfusion reserve through the subtraction of labeled and non-labeled images. Imperfect subtraction caused by cardiac or respiratory motion will lead to measurement error. In this work, we examine the potential for myocardial background suppression using a saturation-double-inversion-recovery preparation that is compatible with ASL experiments. In six volunteers, myocardial signal was suppressed to 1.14% 1.24% of its equilibrium value.