Abstract #0008
Alterations in cerebral physiology in women suffering from anorexia nervosa
Min Sheng 1 , Carrie J. McAdams 2 , Peiying Liu 1 , Binu P. Thomas 1 , and Hanzhang Lu 1
1
Advanced Imaging Research Center, University
of Texas Southwestern Medical Center, Dallas, Texas,
United States,
2
Department
of Psychiatry, University of Texas Southwestern Medical
Center, Dallas, Texas, United States
Anorexia nervosa (AN) is a fatal psychiatric disorder. A
better understanding of physiological changes in AN
patients may help provide a brain-specific health
marker, guide treatment, and predict risk for future
conditions. In this report, we conducted a systematic
study on potential physiological deficits in
currently-ill and long term weight-recovered anorexia
patients. It appears that, the currently-ill patients
receive reduced oxygen delivery to the brain, but the
brain compensates for this small reduction. For the
recovered patients, they still receive less blood supply
to the brain and extract a larger fraction of oxygen
from incoming blood to meet their metabolic demand.
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