Abstract #0039
Hybrid PET/MRI incorporating Dynamic 18F-FDG PET Imaging: Correlation with Biopsy Findings-Preliminary Observations
Andrew B Rosenkrantz 1 , Anne-Kristin Vahle 1 , Christian Geppert 2 , Christopher Glielmi 2 , Fabio Ponzo 1 , Kent P Friedman 1 , Samir S Taneja 3 , Yu-Shin Ding 1 , and Thomas Koesters 1
1
Center for Advanced Imaging
Innovation and Research, Department of
Radiology, NYU Langone Medical Center, New York,
NY, United States,
2
Siemens
Healthcare, Erlangen, Germany,
3
Urologic
Oncology, NYU Langone Medical Center, New York,
New York, United States
This pilot study of 12 prostate cancer patients
explores associations between metrics obtained
from PET/MRI incorporating dynamic 18F-FDG PET
imaging and biopsy findings. DCE-MRI and dynamic
PET were performed simultaneously following
sequential injections of gadolinium-chelate and
FDG. Dynamic PET data was reconstructed in
30-second bins for the first 5 minutes, followed
by 5-minute bins for the remainder of a
30-minute acquisition. Peak and 30-minute FDG
activity were determined from FDG
time-activity-curves and compared among benign
and low- and high-grade tumors. The peak FDG
activity showed the strongest association with
biopsy results, supporting the value of dynamic
PET imaging during PET/MRI.
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