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Abstract #0074

Development of visual cortex in infants

Laura Biagi 1 , Sofia Allegra Crespi 2,3 , Michela Tosetti 1 , and Maria Concetta Morrone 1,4

1 IRCCS Stella Maris Foundation, Calambrone, Pisa, Italy, 2 Department of Psychology, Vita-Salute San Raffaele University, Milan, Italy, 3 CERMAC and Neuroradiology Unit, San Raffaele Hospital, Milan, Italy, 4 Department of Translational Research on New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy

There is little information about the developmental timelines of the cortical areas comprising the neural network that analyses visual motion. We measured at 1.5T cortical bold response in 11 full-term awake 7-weeks-old infants, contrasting coherent flow motion to blank or random noise. Areas MT and V6 respond well to motion at 7 weeks. Correlation analysis suggests weak connectivity between V1 and MT in young infants, but a stronger functional connectivity between the cuneus/MT and V6. The fast development and immature connectivity between V1 and MT points to a possible alternative V1-independent input to MT.

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