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Abstract #0081

Substructural Topographic Map of the Interhemispheric-Cortices Connectivity in Neonate Boys And Girls.

Malek I Makki 1 and Cornelia Hagmann 2

1 MRI Research, University Children Hospital of Zurich, Zurich, Switzerland, 2 Neonatalogy, University Hospital of Zurich, Zurich, Switzerland

Using fiber tracking we draw a topographic map of the interhemispheric-cortices pathways in healthy neonates by segmenting the corpus callosum in 5 substructures: genu, rostral body, body, isthmus and splenium. The connectivity of the genu and rostrum to premotor cortex, the body to the motor cortex as well as the splenium to occipital and temporal occipital lobes were more developed in girls compared to boys (significantly lower mean and radial diffusions in girls). The isthmus connectivity to the superior temporal and posterior parietal is similar in both groups and is the last substructure to develop (lowest anisotropy, and axial diffusion).

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