Abstract #0086
Rapid QSM Acquisition with Wave-CAIPI
Berkin Bilgic 1 , Borjan Gagoski 2 , Stephen Cauley 1 , Audrey Fan 3 , Jonathan Polimeni 1 , Ellen Grant 2 , Lawrence Wald 1 , and Kawin Setsompop 1
1
Martinos Center for Biomedical Imaging,
Charlestown, MA, United States,
2
Boston
Children's Hospital, Boston, MA, United States,
3
EECS,
MIT, Cambridge, MA, United States
Wave-CAIPI acquisition enables highly accelerated
parallel imaging with low g-factor penalty in a 3D
gradient echo (GRE) scan by using i) 2D CAIPIRINHA
controlled aliasing and ii) additional sinusoidal Gy and
Gz encoding gradients during the readout of each phase
encoding line. Herein, data acquisition and
reconstruction time of QSM are dramatically reduced by
the combination of Wave-CAIPI acquisition and fast phase
processing and QSM algorithms. For Wave-CAIPI
reconstruction, we extend the initial proposal by i)
reducing the Wave reconstruction time 25 (from 360 min
to 14 min), ii) estimating accurate point spread
functions from a fast prior training acquisition, and
iii) increasing the resolution 4-fold. This enables high
quality whole-brain 7T QSM at 112 mm3 voxel size in 40
seconds.
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