New Pulse Sequence Combining Diffusion MRI and MR Elastography (dMRE)

Here we introduce a new pulse sequence, Diffusion-MRE (dMRE), for concurrent MRE and diffusion MRI. In dMRE shear motion and diffusion attenuation are encoded into the MR phase and magnitude by using a pair of bipolar gradients. The sequence timing is adjusted so that the bipolar gradients are sensitive to both coherent and incoherent intravoxel motion. The phantom results showed that simultaneous MRE and diffusion acquisition is feasible with no interference between MRE/diffusion acquisitions. The dMRE method may play a role in improving the use of MRE and diffusion for the detection of the diseases in liver and brain.

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