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Abstract #0138

Agreement of 2-, 3-, 4-, 5- and 6-echo MRI-PDFF with MRS-PDFF in 580 adults with known or suspected non-alcoholic fatty liver disease (NAFLD)

Elhamy R Heba 1 , Claude B Sirlin 2 , Tanya Wolfson 3 , Anthony Gamst 3 , Rohit Loomba 4 , and Michael S Middleton 2

1 Radiology, UCSD, san diego, CA, United States, 2 Radiology, UCSD, San Diego, CA, United States, 3 UCSD, San Diego, CA, United States, 4 Internal medicine, UCSD, San Diego, CA, United States

This study was done to compare the agreement of different MRI-PDFF liver fat quantification analysis methodologies in 580 adults with known or suspected non-alcoholic fatty liver disease (NAFLD), using MRS-PDFF as reference standard. We found that 3-, 4-, 5- and 6-echo MRI accurately quantify hepatic PDFF in adults, with 3-echo MRI informally showing the closest and 2-echo MRI the worst agreement.

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