Quantifying variability in DCEMRI of the breast between 1.5T and 3T
Federico D. Pineda 1 , Milica Medved 1 , Xiaobing Fan 1 , Marko Ivancevic 2 , Hiroyuki Abe 1 , Akiko Shimauchi 1 , Charlene Sennet 1 , Gillian Newstead 1 , and Gregory S. Karczmar 1
Radiology, The University of Chicago,
Chicago, IL, United States,
DCEMRI of the breast is a valuable tool in the detection
and staging of breast cancer. Radiologists rely on
measures of uptake and washout of contrast media by
analyzing the signal enhancement of suspicious lesions.
Signal enhancement can vary due to scanner and
acquisition parameters. Eleven volunteers were scanned
at both 1.5T and 3T to quantify the variability in
signal enhancement measures. We found that SER and time
to peak enhancement had the lowest variability.
Conversion from signal enhancement to concentration of
contrast media did not significantly reduce variability,
likely due to B1 inhomogeneity and uncertainty in native
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