Abstract #0228
Medication with Stimulants Modifies the Mean Diffusivity in Children with Attention Deficit/Hyperactivity Disorder: a DTI Study
Rodrigo de Luis-Garcia 1 , Gemma Cabus-Pinol 2 , Carlos Imaz-Roncero 2 , Daniel Argibay-Quinones 1 , Gonzalo Barrio-Arranz 1 , Santiago Aja-Fernandez 1 , and Carlos Alberola-Lopez 1
1
Laboratorio de Procesado de Imagen,
Universidad de Valladolid, Valladolid, Valladolid,
Spain,
2
Hospital
Clinico Universitario, Valladolid, Valladolid, Spain
The impact of ADHD on white matter connectivity has not
been well stablished yet, and the effects of treatment
on the brain structure have not been sufficiently
explored. We investigated the effects of ADHD and
treatment with methylphenidate in the white matter of
children using a tractography selection method that
allows the robust extraction of several fiber bundles of
interest. Differences in the Mean Diffusivity were found
between ADHD patients under treatment and normal
controls and between ADHD patients under treatment and
drug-naive ADHD patients, indicating that the use of
psychostimulants may modify the brain connectivity.
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