Abstract #0271
NODDI performs better than DTI in brain tumors with vasogenic edema
Matteo Figini 1,2 , Giuseppe Baselli 1 , Marco Riva 3 , Lorenzo Bello 4,5 , Hui Zhang 6 , and Alberto Bizzi 7
1
Dipartimento di Elettronica, Informazione e
Bioingegneria, Politecnico di Milano, Milano, MI, Italy,
2
Scientific
Direction, Fondazione IRCCS Istituto Neurologico "Carlo
Besta", Milano, MI, Italy,
3
Neurosurgery,
Universit degli Studi di Milano, Milano, MI, Italy,
4
Surgical
Neuro-Oncology Unit, Humanitas Clinical and Research
Center, Rozzano, MI, Italy,
5
Department
of Medical Biotechnology and Translational Medicine,
Universit degli Studi di Milano, Milano, MI, Italy,
6
Department
of Computer Science and Centre for Medical Image
Computing, University College London, London, United
Kingdom,
7
Neuroradiology, Humanitas Clinical
and Research Center, Rozzano, MI, Italy
In this work we developed a procedure to perform NODDI-based
tractography with an ODI threshold equivalent to the
commonly used FA = 0.2 in order to fairly compare the
results with those from DTI-based tractography; the aim
is to investigate the advantages of performing
tractography based on fiber directions and
microstructural parameters estimated by NODDI. Our
preliminary results showed a higher track density in
areas infiltrated by brain tumours with NODDI than with
DTI. The advantage of NODDI-based tractography appears
to be most evident in areas of vasogenic edema.
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