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Abstract #0272

A comparative study of 16 tractography algorithms for the corticospinal tract: reproducibility and subject-specificity

Emmanuel Caruyer 1 , Luke Bloy 2 , Birkan Tun 1 , Jrmy Lecoeur 1 , Varsha Shankar 1 , and Ragini Verma 1

1 Section of Biomedical Image Analysis, Department of Radiology, University of Pennsylvania, Philadelphia, PA, United States, 2 Children's Hospital of Pennsylvania, Philadelphia, PA, United States

We present a comparative study of 16 fiber tractography algorithms on a test-retest dataset of 9 healthy subjects. We evaluate the ability of the tractography methods to provide reproducible tracts geometries, as well as to reconstruct subject-specific white matter anatomy. The dataset consists in 9 healthy subjects, scanned at three time points separated by a 2 weeks interval. We reconstructed both left and right corticospinal tracts. Tractography algorithms were tested using either their freely available implementations or in house software. We report contrasted results across tracking methods.

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