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Abstract #0273

How should tractography go forward? A Tractometer evaluation of local reconstruction and tracking

Jean-Christophe Houde 1 , Emmanuel Caruyer 2 , Alessandro Daducci 3 , and Maxime Descoteaux 1

1 Computer Science Departement, Universit de Sherbrooke, Sherbrooke, Qubec, Canada, 2 Department of Radiology, University of Pennsylvania, Pennsylvania, United States, 3 Signal Processing Lab (LTS5), cole polytechnique fdrale de Lausanne (EPFL), Lausanne, Switzerland

The Tractometer evaluation system is presented. We show how it was used to evaluate entries in the ISBI 2013 HARDI reconstruction challenge. From this evaluation, important questions about local modeling and tractography arose, such as: for the tractography end user, what is really important? More precise local reconstructions? Tracking algorithms with the least errors, or with the least missed bundles? Is angular error the best quality metric for local model development? How should we deal with errors in tractography? And most critically, how can we evaluate tractography pipelines on real data? These questions, and some insights, are presented in this work.

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