Abstract #0293
Dynamic Oxygen-Enhanced MRI vs. Quantitative Thin-Section CT: Capability for Pulmonary Functional Loss Assessment and Clinical Stage Classification in Asthmatics
Yoshiharu Ohno 1 , Shinichiro Seki 2 , Mizuho Nishio 1 , Hisanobu Koyama 2 , Takeshi Yoshikawa 1 , Sumiaki Matsumoto 1 , Nobukazu Aoyama 3 , Makoto Obara 4 , Marc van Cauteren 5 , Hideaki Kawamitsu 3 , and Kazuro Sugimura 2
1
Advanced Biomedical Imaging Research Center,
Kobe University Graduate School of Medicine, Kobe,
Hyogo, Japan,
2
Radiology,
Kobe University Graduate School of Medicine, Kobe,
Hyogo, Japan,
3
Center
for Radiology and Radiation Oncology, Kobe University
Hospital, Kobe, Hyogo, Japan,
4
Philips
Electronics Japan, Tokyo, Japan,
5
Philips
Healthcare Asia Pacific, Tokyo, Japan
Dynamic O2-enhanced MRI is suggested as useful for
separate assessments of regional ventilation and oxygen
transfer in smokers. However, there are no reports about
capability of assessment of dynamic O2-enhanced MRI for
pulmonary functional loss assessment and clinical stage
classification in asthmatics. We hypothesized that
dynamic O2-enhanced MRI has potential for functional
loss assessment and clinical stage classification in
asthmatics as well as quantitatively assessed
thin-section CT. The purpose of the study reported here
was to prospectively and directly compare the efficacy
of dynamic O2-enhanced MRI and quantitative CT for
functional loss assessment and clinical stage
classification in asthmatics.
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