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Abstract #0294

Oxygen-enhanced T1-mapping MRI of the lung in patients with chronic lung-allograft dysfunction

Jens Vogel-Claussen 1 , Julius Renne 1 , Peer Lauermann 1 , Jan Hinrichs 1 , Christian Schnfeld 1 , Sajoscha Sorrentino 1 , Marcel Gutberlet 1 , Peter Jakob 2 , Axel Haverich 1 , Gregor Warnecke 1 , Tobias Welte 1 , Frank K Wacker 1 , and Jens Gottlieb 1

1 Hannover Medical School, Hannover, Niedersachsen, Germany, 2 University of Wrzburg, Wrzburg, Germany

Oxygen-enhanced T1 mapping MRI of the lung is capable of detecting pulmonary alterations occurring in patients with chronic lung rejection after transplantation. The coefficient of variation and T1 between room air and 100% oxygen may serve as novel biomarkers for early bronchiolitis obliterans syndrome (BOS).

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