Abstract #0295
3D pulmonary perfusion MRI with radial ultra-short echo time and spatial-temporal constrained reconstruction
Grzegorz Bauman 1 , Kevin M Johnson 1 , Laura C Bell 1 , Julia V Velikina 1 , Alexey A Samsonov 1 , Scott K Nagle 1,2 , and Sean B Fain 1,2
1
Department of Medical Physics, University of
Wisconsin-Madison, Madison, WI, United States,
2
Department
of Radiology, University of Wisconsin-Madison, Madison,
WI, United States
In this work we present a novel DCE MRI technique that
combines a time-resolved 3D UTE acquisition with
constrained reconstruction for assessment of regional
lung perfusion. High isotropic spatial resolution is
achieved by acquiring undersampled data for each time
frame and reconstructing it using dimensionality
reduction in temporal domain via principal component
analysis and wavelet soft-thresholding in spatial
domain. We present feasibility of this technique in
simulations using a fractal-based digital lung phantom
and in vivo experiment in a human subject.
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