Abstract #0302
Comparison of Quantitative T 2 Mapping Techniques for Articular Cartilage
Stephen J. Matzat 1 , Emily J. McWalter 1 , Feliks Kogan 1 , Weitian Chen 2 , and Garry E. Gold 1,3
1
Radiology, Stanford University, Stanford,
CA, United States,
2
MR
Applied Science Laboratory, GE Healthcare, Menlo Park,
CA, United States,
3
Bioengineering, Stanford
University, Stanford, CA, United States
New MR pulse sequences provide faster methods for T
2
mapping
of articular cartilage, yet each method may introduce a
bias in T
2
quantitation.
The present study analyzes quantitative outcomes from
six MR sequences for
in
vivo
T
2
mapping
of patellar, femoral, and tibial cartilage, using single
echo spin echo as a reference standard. Some sequences
exhibited a consistent bias in T
2
measurements
while others demonstrated varied bias along the range of
T
2
values.
Overall variation between sequences was appreciable and
highlights the importance of further study of these
differences.
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