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Abstract #0328

Image quality characterization in Time-Resolved 3D CE-MRA

Yijing Wu 1 , Kevin M Johnson 1 , Jane H Maksimovic 2 , Charles A Mistretta 1 , and Patrick A Turski 2

1 Medical Physics, University of Wisconsin, Madison, WI, United States, 2 Radiology, University of Wisconsin, Madison, WI, United States

Time-resolved 3D contrast-enhanced MR angiography (CE-MRA) often requires highly accelerated imaging to achieve clinically desired temporal and spatial resolutions. Recently developed non-linear reconstruction schemes, e.g. compressed sensing (CS) and HYPR, offer substantially greater acceleration than past methods but are unfortunately inherently object dependent and difficult to characterize with traditional linear methods. Subsequently, exemplary results in simplified digital phantoms do not translate clinically. In this work, we investigate the use of a highly realistic fractal based digital imaging phantom for accurate characterization of several non-linear reconstructions (CS, HYPR, and CS-HYPR).

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