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Abstract #0329

Towards Robust Breath-held 3D Abdominal DCE Imaging

Nadine Gdaniec 1 , Andrea J. Wiethoff 2,3 , Qing Yuan 4 , Peter Brnert 5 , Holger Eggers 5 , Daniella Pinho 4 , Ivan Pedrosa 3,4 , and Alfred Mertins 1

1 Institute for Signal Processing, University of Luebeck, Luebeck, Luebeck, Germany, 2 Philips Research North America, Briarcliff Manor, New York, United States, 3 Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, Texas, United States, 4 Department of Radiology, UT Southwestern Medical Center, Dallas, Texas, United States, 5 Philips Research Laboratories, Hamburg, Hamburg, Germany

Image quality in clinical dynamic contrast enhanced (DCE) MRI of the abdomen is often degraded by respiratory motion artifacts, making diagnosis difficult. Breath-holding is an efficient strategy to minimize respiration induced artifacts in the abdomen if the patients capability is sufficient. In many cases, patients have trouble holding their breath after contrast injection, even if they were able to do so earlier in the exam. To overcome this problem, DCE imaging with flexible scan termination is proposed in this work, to automatically adapt to the breath-hold capabilities of the patient. Shorter breath-holds are compromised with lower but adapted spatial resolution.

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