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Abstract #0330

Free Breathing Dynamic Contrast Enhanced 3D MRI with Resolved Respiratory Motion

Joseph Y. Cheng 1,2 , Tao Zhang 1 , John M. Pauly 1 , Shreyas S. Vasanawala 2 , and Michael Lustig 3

1 Electrical Engineering, Stanford University, Stanford, California, United States, 2 Radiology, Stanford University, Stanford, California, United States, 3 Electrical Engineering & Computer Sciences, University of California, Berkeley, California, United States

Respiratory motion is a major hindrance in abdominal MRI. Previous work has been focused on reducing respiratory motion artifacts through correction schemes in the image reconstruction. An alternative approach is resolving the respiratory motion. We propose to correct for respiratory motion in free breathing DCE-MRI by extending the data-acquisition space to an additional respiratory dimension. The highly undersampled 5D-dataset is reconstructed by promoting the locally low-rank property in the DCE dimension and the total variation penalty in the respiratory motion dimension. The proposed technique achieves similar image quality to a DCE-only reconstruction and a lightly undersampled respiratory motion resolved reconstruction.

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