Quantifying the contribution of white matter microstructure to frequency contrast in gradient echo MRI

In most studies involving GE phase imaging, it is assumed that the dominant source of phase contrast is the variation in magnetic susceptibility across different tissues. Recent studies have suggested that white matter microstructure may be an additional source of phase contrast. In this study, we quantify the frequency contribution of white matter microstructure in a small tissue phantom by using sophisticated simulation techniques to model and remove the frequency contribution of bulk isotropic and anisotropic magnetic susceptibility. This approach also yields accurate estimates of the isotropic (-82 ppb) and anisotropic (11 ppb) susceptibility of white matter.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.