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Abstract #0434

Regional Frank-Starling relations in infarcted swine via dynamic real-time MRI

Francisco Contijoch 1 , Walter RT Witschey 1 , Jeremy McGarvey 1 , Madonna Lee 1 , Norihiro Kondo 1 , Toru Shimaoka 1 , Chikashi Aoki 1 , Satoshi Takebayashi 1 , Gerald A Zsido 1 , Christen Dillard 1 , Joseph H Gorman 1 , Robert C Gorman 1 , and James J Pilla 1

1 University of Pennsylvania, Philadelphia, PA, United States

Current imaging methods provide non-invasive and high spatial resolution approach, but are load-dependent since values obtained are influenced by the end-diastolic volume (preload) and arterial impedance (afterload). In this work, we developed an MRI method to quantify regional response to alterations in preload. As a result, we obtain regional Frank-Starling relations in infarcted swine.

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