Abstract #0435
Complete functional assessment of the mouse heart with one-minute acquisition
Guido Buonincontri 1 , Carmen Methner 2 , Thomas Krieg 2 , T Adrian Carpenter 1 , and Stephen J Sawiak 1,3
1
Wolfson Brain Imaging Centre, Department of
Clinical Neurosciences, University of Cambridge,
Cambridge, United Kingdom,
2
Department
of Medicine, University of Cambridge, Cambridge, United
Kingdom,
3
Behavioural
and Clinical Neuroscience Institute, University of
Cambridge, Cambridge, United Kingdom
Long scan duration limits the usage of cine MRI methods
in mice. We employed spatiotemporal compressed sensing
and parallel imaging to accelerate retrospectively-gated
cine MRI of mouse hearts. We found that the scan time
for the whole heart could be reduced to one minute when
using radial sampling. The accuracy in the estimation of
left and right ventricular volumes was preserved for all
tested subjects. This method can be used to perform fast
and accurate functional MRI exams in mice.
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