Abstract #0454
Multiparametric functional MRI for assessment of delayed renal allograft function
Dagmar Hartung 1,2 , Marcel Gutberlet 1,2 , Frank Lehner 2,3 , Nicolas Richter 3 , Nils Hanke 4 , Jan Becker 2,5 , Matti Peperhove 1 , Antonia Zapf 6 , Hermann Haller 4 , Frank Wacker 1 , Wilfried Gwinner 2,4 , and Katja Hueper 1,2
1
Radiology, Hannover Medical School,
Hannover, Germany,
2
Integrated
Research and Treatment Center Transplantation (IFB Tx),
Hannover, Germany,
3
Transplantation Surgery,
Hannover Medical School, Hannover, Germany,
4
Nephrology,
Hannover Medical School, Hannover, Germany,
5
Pathology,
Hannover Medical School, Hannover, Germany,
6
Medical
Statistics, University Goettingen, Goettingen, Germany
Delayed renal allograft function (DGF) is associated
with an increased risk of graft complications. We
investigated whether multiparametric functional MRI
allows evaluation of DGF. Fourty patients between day
4-10 after kidney transplantation were examined using a
1.5T-scanner. Renal perfusion, apparent diffusion
coefficients and fractional anisotropy were
significantly reduced in patients with DGF compared to
patients with normal initial graft function.
Furthermore, functional MRI parameters were inversely
correlated with serum creatinine at the day of MRI and
at 3-months follow-up. Thus, multiparametric functional
MRI may improve non-invasive diagnosis of DGF.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
