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Abstract #0466

Default Mode Network (DMN) Activity during Olfactory Processing

Prasanna Karunanayaka 1 , Megha Vasavada 1 , Michael Tobia 1 , Jianli Wang 1 , Paul Eslinger 2 , and Qing X Yang 1

1 Radiology, Penn State University, Hershey, Pennsylvania, United States, 2 Neurology, Penn State University, Hershey, Pennsylvania, United States

Default mode Network modulations during olfactory processing can provide valuable information since both networks are implicated in higher-order cognitive processing. Network deactivation refers to a relatively higher level of neural activity during rest conditions (or low demand tasks) compared to active (or high-demand) conditions. Using olfactory fMRI, we provide direct evidence to 1) support DMN deactivation during odor stimulation and 2) establish a functional connection between olfactory and DMN networks to suggest a role for higher-order cognitive processing for olfaction.

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