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Abstract #0510

Ultrashort Echo Time Magnetization Transfer (UTE-MT) Imaging of Cortical Bone

Jiang Du 1 , Shihong Li 1 , Won Bae 1 , Reni Biswas 1 , Sheronda Statum 1 , Eric Chang 1 , and Christine B Chung 1

1 Radiology, University of California, San Diego, San Diego, CA, United States

Magnetization transfer (MT) imaging is one way of indirectly assessing pools of protons with extremely fast transverse relaxation. However, conventional long TE MT imaging sequences are not applicable to short T2 tissues such as cortical bone. Ultrashort echo time (UTE) sequences can detect signal from short T2 species. The combination of UTE with MT (UTE-MT) provides a valuable option to assess different bone components. In this study we evaluated UTE-MT imaging of cortical bone and its application in assessing cortical porosity and biomechanical properties of cadaveric human bone samples using a clinical whole body 3T scanner.

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