Abstract #0516
Comprehensive Hemodynamic Evaluation of Intracranial Atherosclerotic Disease with 4D Flow MR Imaging
Can Wu 1 , Shyam Prabhakaran 2 , Timothy Carroll 1,3 , Parmede Vakil 3 , Neil Chatterjee 1,3 , Amir Honarmand 3,4 , Sameer Ansari 3,4 , James Carr 3 , and Michael Markl 1,3
1
Biomedical Engineering, Northwestern
University, Chicago, IL, United States,
2
Neurology,
Northwestern University, Chicago, IL, United States,
3
Radiology,
Northwestern University, Chicago, IL, United States,
4
Neurological
Surgery, Northwestern University, Chicago, IL, United
States
The purpose of this study was to evaluate the
feasibility of 4D flow MR imaging for the comprehensive
evaluation of intracranial hemodynamics in 20 patients
with intracranial atherosclerotic disease (ICAD)
including quantitative analysis of peak velocity and
mean blood flow in the large intracranial vessels. The
results demonstrated significant impact of regional
stenotic lesions on the hemodynamics in systemic
vascular territories. Combined evaluation of the
qualitative visualization of the blood flow patterns and
distribution of blood flow velocities and quantitative
hemodynamic markers may provide additional insight into
the pathophysiology and risk stratification for ICAD
patients.
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