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Abstract #0517

Comparison of digital subtraction angiography with 3D high-resolution MR vessel wall imaging for the evaluation of basilar artery atherosclerotic stenosis and plaque distribution

Aofei Liu 1 , Xihai Zhao 2 , Huijun Chen 2 , Zhensen Chen 2 , William Kerwin 3 , Chun Yuan 2,3 , Bin Du 1 , and Wei-Jian Jiang 1

1 New Era Stroke Care and Research Institute, The Second Artillery General Hospital PLA, Beijing, China, 2 Center for Biomedical Imaging Research & Department of Biomedical Engineering, Tsinghua University, Beijing, China, 3 Department of Radiology, University of Washington, Seattle, WA, United States

We sought to compare DSA and MR vessel wall imaging in evaluating the degree of stenosis and plaque distribution in BA. Of 31 subjects, the stenotic degree measured by DSA and MRI was 32.9% and 42.9% respectively. Excellent agreement was found between DSA and MRI in stenosis measurement (r=0.898, P<0.001). DSA underestimated the degree of luminal stenosis, which may be due to its limitation in viewing eccentrically stenotic lesion. The incidence of plaque affecting each quadrant on MRI is greater than that of DSA, suggesting MR vessel wall imaging may be a better imaging modality to evaluate lesion distribution in BA.

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