Abstract #0527
Automated correction method allowing phase-based detection of contrast enhancement in DCE-MRI
Ellis Beld 1 , Frank F.J. Simonis 1 , Johannes G. Korporaal 1 , Uulke A. van der Heide 2 , and Cornelis A.T. van den Berg 1
1
Radiotherapy, UMC Utrecht, Utrecht,
Netherlands,
2
Radiotherapy,
Netherlands Cancer Institute - Antoni van Leeuwenhoek
Hospital (NKI-AVL), Amsterdam, Netherlands
Phase-sensitive MR procedures are affected by spatially
and temporally varying B0 inhomogeneities. A higher
order background phase correction, to compensate for
these inhomogeneities, was used for phase-based
measurement of the arterial input function (AIF) in
dynamic contrast-enhanced (DCE) MRI. The background
phase was calculated inwards from the subcutaneous fat
layer, using a near-harmonic 2D reconstruction. Besides
measurement of the AIF, the background corrected phase
data enables detection of contrast induced phase
modulation in tissues.
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