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Abstract #0564

Assessment of fetal lung maturation from diffusion weighted MRI at 3T

Onur Afacan 1 , Ali Gholipour 1 , Robert V. Mulkern 1 , Carol Barnewolt 2 , Sigrid Bairdain 3 , Judy Estroff 2 , Susan Connolly 2 , and Simon K. Warfield 1

1 Department of Radiology, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts, United States, 2 Advanced Fetal Care Center, Department of Radiology, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts, United States, 3 Department of Surgery, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts, United States

The aim of the study is to establish the normal range of fetal lung diffusion values measured at 3T in fetuses with normal lung development. We have found a high correlation between ADC and gestational age in fetuses with normal lung development. This study will help to determine whether the diffusion coefficient can be used to assess fetal lung development, which may lead to an improved understanding of the risk factors for adverse outcome, and ultimately facilitate successful fetal intervention in fetuses most at risk of adverse outcome.

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