Abstract #0598
HARPERELA Phase Processing for Quantitative Susceptibility Mapping
Wei Li 1,2 , Alexandru V Avram 1,3 , Bing Wu 1,4 , Xue Xiao 1,5 , and Chunlei Liu 1,6
1
Brain Imaging and Analysis Center, Duke
University, Durham, NC, United States,
2
Research
Imaging Institute, University of Texas Health Science
Center at San Antonio, San Antonio, TX, United States,
3
National
Institute of Health, Bethesda, DC, United States,
4
GE
Healthcare, Beijing, China,
5
Tsinghua
University, Beijing, China,
6
Radiology,
Duke University, Durham, NC, United States
3D phase unwrapping and background phase removal are
typically two separated preprocessing steps for
quantitative susceptibility mapping (QSM). We developed
a novel method for integrated phase unwrapping and
harmonic background phase removal using Laplacian, named
as HARPERELLA. HARPERELLA is fast, robust, easily to
implement and yields local tissue phase with similar
accuracy to that using the well-known SHARP and PDF
methods. To facilitate evaluation and dissemination, we
combined HARPERELLA, QSM, susceptibility tensor imaging
(STI) algorithms and related graphical user interfaces
into a software package, named as STI Suite, which is
available online for free academic use.
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