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Abstract #0603

Slab Segmented Edge-preserving QSM Method

Fei Cong 1 , Bo Wang 1 , Xiaohong Joe Zhou 2 , Yan Zhuo 1 , and Yongquan Ye 3

1 Institute of Biophysics, Chinese Academy of Sciences, Chaoyang District, Beijing, China, 2 Department of Radiology and Center for MR Research, University of Illinois Medical Center, Chicago, IL, United States, 3 Department of Radiology, School of Medicine, Wayne State University, Detroit, MI, United States

A new edge-preserving method for quantitative susceptibility mapping (QSM) is proposed, which uses 3D slab segmented Wiener filtered phase data as input and the convex half-quadratic regularizing algorithm to suppress the artifacts when solving the inverse problem by using ill-conditioned Greens function kernel. Compared to current QSM methods, this edge-preserved method reserves the high spatial frequency details for veins in the final susceptibility maps. The comparisons between quadratic regularized and edge-preserved methods of the whole brain are presented, and the feasibility and future work are discussed.

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