The best of both worlds: Improved rapid quantitative susceptibility mapping (QSM) by combining closed-form L2 regularization with SDI
Ferdinand Schweser 1 , Andreas Deistung 1 , Xiang Feng 1 , Edsel Daniel Peres Gomez 2 , and Jrgen R Reichenbach 1
Medical Physics Group, Institute of
Diagnostic and Interventional Radiology I, Jena
University Hospital - Friedrich Schiller University
Jena, Jena, Germany,
Physics Group, Institute of Diagnostic and
Interventional Radiology I, Jena University Hospital -
Friedrich Schiller University Jena, Germany
Quantitative susceptibility mapping (QSM) is a novel
post-processing technique for gradient-echo phase data.
Schweser et al. have recently presented that inverse
filtering with extreme thresholding of the unit dipole
response (SDI) yields within seconds susceptibility maps
without noise amplification and with a low level of
streaking artifacts. Bilgic et al. recently presented a
closed-form solution for rapid L2-regularized QSM with a
gradient-based penalty (CF-L2) that provides images with
even reduced noise level compared to SDI . In this
contribution, we show that combining CF-L2 with SDI can
considerably reduce reconstruction artifacts.
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