Abstract #0606
A joint background field removal and dipole deconvolution approach for quantitative susceptibility mapping in the liver
Samir D. Sharma 1 , Diego Hernando 1 , Debra E. Horng 1 , and Scott B. Reeder 1,2
1
Radiology, University of Wisconsin -
Madison, Madison, WI, United States,
2
Medical
Physics, University of Wisconsin - Madison, Madison,
Wisconsin, United States
Noninvasive quantification of liver iron concentration
is important for the detection and staging of iron
overload as well as for effective longitudinal
monitoring during treatment. Magnetic susceptibility is
a fundamental property of tissue that has a well-defined
relationship to iron concentration. Quantitative
susceptibility mapping (QSM) methods have been developed
in the brain to quantify the concentrations of localized
iron deposits. The purpose of this work was to develop a
QSM technique for the liver and to demonstrate its
feasibility for measuring susceptibility in the liver,
which may serve as an imaging biomarker of liver iron
overload.
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