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Abstract #0611

Non-Cartesian Navigation for Subspace 3D Myocardial Perfusion Imaging

Anthony G. Christodoulou 1 , Yijen L. Wu 2 , T. Kevin Hitchens 2 , Chien Ho 2 , and Zhi-Pei Liang 1

1 Department of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, IL, United States, 2 Pittsburgh NMR Center for Biomedical Research, Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA, United States

We investigate 2D and 3D non-Cartesian k-space navigator trajectories for low-rank (subspace) myocardial perfusion imaging, replacing 1D Cartesian navigators (which are highly sensitive to readout direction). A rodent ischemic re-perfusion injury animal model was used for both whole-heart 3D first-pass and delayed myocardial perfusion imaging in rats. The resulting 3D images have high spatiotemporal resolution (128 x 128 x 24 matrix size, 0.31mm x 0.31mm x 1.0 mm spatial resolution, 74 frames per second) and were used for analysis of both the first-pass of contrast and of late enhancement.

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