Abstract #0679
Transperineal in-bore 3T MRI guided prostate biopsy in active surveillance patients: Higher prevalence of anteriorly located positive prostate cancer targets
Tobias Penzkofer 1,2 , Kemal Tuncali 1 , Fiona M Fennessy 1,3 , Junichi Tokuda 1 , Andriy Fedorov 1 , Sang-Eun Song 1 , Nobuhiko Hata 1 , and Clare M Tempany 1
1
Radiology, Brigham and Women's Hospital,
Boston, MA, United States,
2
Diagnostic
and Interventional Radiology, RWTH Aachen University
Hospital, Aachen, Germany,
3
Radiology,
Dana Farber Cancer Institute, Boston, MA, United States
Based on the known impact of prostate cancer
localization within the gland on the success rate of
guided prostate biopsy, we assessed the influence of
target localization on positivity rate in a cohort of 20
patients in an active surveillance setting. Using
in-bore transperineal MRI-guided prostate biopsy we
found that anterior prostate gland targets have a
significantly higher cancer yields than any other
location in the gland when biopsied using this
transperineal access, with a markedly lower number of
cores compared to template mapping biopsy. This data
could impact biopsy strategies and decision making in
the active surveillance setting.
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