Compression Effects in Breast MR Elastography

In conventional breast MR Elastography (MRE), the driver compresses the breasts to maintain mechanical coupling for wave transmission. This compression could introduce a significant bias into the measured stiffness of breast tissue. For the first time, this study reports strong evidence of breast compression effects in breast MRE. With 20% breast compression, glandular and adipose tissue stiffness increased by 53.8% and 103.8% respectively. Therefore, true breast tissue stiffness can be measured only when there is no compression, such as when using the noncompressive breast MRE technique utilized in this study.

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