Comprehensive Geometric Distortion Correction for Diffusion Tensor Imaging at Ultra-High Field

A well-known problem in echo-planar imaging (EPI) is geometric distortion due to field inhomogeneities induced by susceptibility effects. In diffusion weighted EPI (DW-EPI), in addition, the distortions vary due to eddy-currents from diffusion gradients. To correct both susceptibility and eddy-current induced distortions, a comprehensive approach using the point spread function (PSF) mapping based methods is presented. An extended PSF method with a reversed gradient approach suggested recently was adapted for susceptibility-induced distortion correction, and a fast PSF-based eddy-current calibration method is newly suggested in this study. The combination of the methods thus allows distortion-free DW-EPIs without loss of spatial resolution.

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