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Abstract #0738

Cardiac Diffusion Tensor Imaging: Adaptive Anisotropic Gaussian Filtering to Reduce Acquisition Time

Ria Mazumder 1,2 , Bradley D. Clymer 1 , Richard D. White 2,3 , and Arunark Kolipaka 2,3

1 Department of Electrical and Computer Engineering, The Ohio State University, Columbus, OH, United States, 2 Department of Radiology, The Ohio State University, Columbus, OH, United States, 3 Department of Internal Medicine-Division of Cardiology, The Ohio State University, Columbus, OH, United States

The counter-directional helical structure of the heart plays an important role in regulating cardiac mechanics and can be quantified on the basis of the angle it subtends known as helical angle (HA). Non-invasive measurement of HA is possible using diffusion tensor imaging, the accuracy of which is dependent on increased diffusion encoding directions (DED) and high signal to noise ratio (i.e. increase in averages). The purpose this study is to robustly estimate HA using fewer averages and DED (thereby, reducing the acquisition time) by implementing a 3D adaptive anisotropic Gaussian post-processing filter.

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