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Abstract #0771

Introduction of global specific ventilation as a reference for specific ventilation derived by Fourier Decomposition MRI

Andreas Voskrebenzev 1 , Marcel Gutberlet 1 , Lena Becker 1 , Julius Renne 1 , Jan Hinrichs 1 , Christian Schnfeld 1 , Sajoscha Sorrentino 1 , Frank Wacker 1 , and Jens Vogel-Claussen 1

1 Radiology, Medical School Hannover, Hannover, Lower Saxony, Germany

Fourier Decomposition (FD) is a method to calculate ventilation-weighted images of the lung without the need of any contrast agent. These images can be used to determine the dimensionless specific ventilation (SV). We introduce the global SV as the ratio of breathing volume change to lung volume during mid-position of respiration. The presented correlation of global and FD SV could be utilized to normalize the SV maps in cross-sectional and longitudinal studies. Thereby, this study shows that the combination of MRI and real-time respiration detection is of relevance for the comparison of absolute SV values.

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