Introduction of global specific ventilation as a reference for specific ventilation derived by Fourier Decomposition MRI
Andreas Voskrebenzev 1 , Marcel Gutberlet 1 , Lena Becker 1 , Julius Renne 1 , Jan Hinrichs 1 , Christian Schnfeld 1 , Sajoscha Sorrentino 1 , Frank Wacker 1 , and Jens Vogel-Claussen 1
Radiology, Medical School Hannover,
Hannover, Lower Saxony, Germany
Fourier Decomposition (FD) is a method to calculate
ventilation-weighted images of the lung without the need
of any contrast agent. These images can be used to
determine the dimensionless specific ventilation (SV).
We introduce the global SV as the ratio of breathing
volume change to lung volume during mid-position of
respiration. The presented correlation of global and FD
SV could be utilized to normalize the SV maps in
cross-sectional and longitudinal studies. Thereby, this
study shows that the combination of MRI and real-time
respiration detection is of relevance for the comparison
of absolute SV values.
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