Abstract #0770
Comparison of regional ventilation defect distribution between oxygen-enhanced and hyperpolarized He-3 MRI
Stanley J Kruger 1 , Scott K Nagle 1,2 , Robert V Cadman 1 , Kevin M Johnson 1,2 , Laura C Bell 1 , Andrew D Hahn 1 , and Sean B Fain 1,2
1
Medical Physics, University of Wisconsin -
Madison, Madison, WI, United States,
2
Radiology,
University of Wisconsin - Madison, Madison, WI, United
States
Oxygen Enhanced MRI with 3D radial ultrashort echo time
(OE-MRI) is an emerging technique for the evaluation of
lung ventilation with advantages over hyperpolarized
noble gas MRI (HP-MRI) in terms of accessibility and
cost effectiveness. Nonetheless, HP-MRI is an emerging
reference standard for pulmonary MRI of ventilation. The
purpose of this work is to compare the heterogeneity of
ventilation as depicted regionally for the same subjects
with HP-MRI and OE-MRI to evaluate regional distribution
of ventilation defects using the respective techniques.
The whole-lung coverage provided by 3D radial OE-MRI
could be readily compared to HP-MRI as a reference
standard.
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