Diffusion-Weighted, Readout-Segmented EPI with Synthesized T2- and T2*-Weighted Images

Readout-segmented EPI (rs-EPI) is an alternative sequence for diffusion-weighted imaging of the brain with less artifact and higher resolution than single-shot EPI. The higher-quality, low-b-value image could in some cases be used to replace a separate T2-weighted acquisition and reduce overall examination time, but the echo time is usually shorter than that used in typical clinical protocols. This study introduces a modification to the sequence, which generates additional T2-weighted images with a user-specified echo time that is suitable for clinical studies. The technique can also provide integrated T2*-weighted images, which may be useful for detecting hemorrhage in acute stroke.

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