DSI 101: Better ODFs for free!

Diffusion Spectrum Imaging (DSI) is a well established method to recover the diffusion propagator (EAP). The orientation distribution function (ODF) is computed from this discretized EAP and used for tractography. However, there are several important implementation considerations that are tossed aside in the literature and the publicly available softwares. We investigate all the real steps necessary to go from the DSI signal to the ODF and provide applicable recommendations that greatly improve the accuracy of the local orientation detected. These recommendations come free-of-charge as they are applicable to all existing DSI data and do not require a significant increase in computation time.

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