Abstract #0814
Measurement of T 2 and T 2 * in Spin Echo Single Point EPR Imaging Using a Single Acquisition Method
Hyungseok Jang 1 , Sankaran Subramanian 2 , Nallathamby Devasahayam 2 , Shingo Matsumoto 2 , Keita Saito 2 , Murali C. Krishna 2 , and Alan B. McMillan 1
1
Radiology, University of Wisconsin, Madison,
WI, United States,
2
Radiation
Biology Branch, Center for Cancer Research, NCI,
National Institutes of Health, Bethesda, MD, United
States
Electron paramagnetic resonance imaging (EPRI) has
surfaced as a promising technique that can allow
quantitative imaging of tissue oxygenation. Owing to the
extremely short spin-spin relaxation time, single point
imaging (SPI) is used, where entire FID is
phase-encoded. Several methods have been proposed to
overcome zoom-in effect inherent in SPI-EPRI. Among
them, spin echo based SPI-EPRI (ESPI-EPRI) is worthy of
study because it can allow simultaneous T
2
and
T
2
* estimation when combined with a single
acquisition method. In this study, the physical and
physiological significance of T
2
and
T
2
* measures was explored through the
proposed single acquisition method in ESPI-EPRI.
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