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Abstract #0825

Single Line Multiple Echo Diffusion Tensor Acquisition Technique: feasibility of dynamic diffusion tensor parameters in a flow phantom and in vivo muscle tissue on a 3T clinical scanner

Steven Baete 1 , Gene Cho 1,2 , Jenny T. Bencardino 3 , and Eric E Sigmund 1

1 Center for Biomedical Imaging, Dept. of Radiology, NYU Langone Medical Center, New York, New York, United States, 2 Sackler Institute of Graduate Biomedical Sciences, NYU School of Medicine, New York, New York, United States, 3 Department of Radiology, NYU Hospital for Joint Diseases, New York, New York, United States

The feasibility of dynamic single line acquisition of diffusion tensor parameters is demonstrated in a flow phantom and in in vivo skeletal muscle on a 3T clinical scanner. This method, Single Line Multiple Echo Diffusion Tensor Acquisition Technique SL-MEDITATE), encodes each of multiple echoes generated by five RF-pulses with different diffusion weighting. A single line is selected by orthogonal slice selective gradients. The resulting dynamic acquisition can be used to study the transient changes in diffusion tensor parameters, such as in muscle tissue following exercise, where traditional DTI methods lack temporal resolution.

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