Abstract #0857
Comprehensive human fetal hemodynamic assessment by phase contrast MRI and MR oximetry
Liqun Sun 1,2 , Joshua van Amerom 3,4 , Mashael Al-Rujaib 1 , Edgar Jaeggi 2 , Lars Grosse Wortmann 2 , Shi-Joon Yoo 1 , Christopher K. Macgowan 3 , and Mike Seed 1
1
Department of Diagnostic Imaging, Hospital
for Sick Children, University of Toronto, Toronto,
Ontario, Canada,
2
Department
of Paediatrics, Division of Paediatric Cardiology,
Hospital for Sick Children, University of Toronto,
Toronto, Ontario, Canada,
3
Departments
of Medical Biophysics and Medical Imaging, Hospital for
Sick Children, University of Toronto, Ontario, Canada,
4
Division
of Imaging Sciences and Biomedical Engineering, Kings
College, London, United Kingdom
We demonstrated evidence of reduced DO2 and VO2 due to
placental insufficiency in a fetus with aortic
coarctation and clinical evidence of fetal distress with
associated hypoxic brain injury that was undetected by
routine clinical monitoring. An unexpected finding was
the lower placental oxygen delivery in fetuses with CHD,
which could be due to abnormal placental development and
function in the setting of CHD.
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