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Abstract #0873

Evaluation of left ventricular diastolic function with cine magnetic resonance imaging: three-dimensional volume tracking of mitral annulus motion

Vincent Wu 1 , Sohae Chung 1 , Sharath Bhagavatula 1 , and Leon Axel 1

1 Department of Radiology, New York University School of Medicine, New York, NY, United States

Cardiac magnetic resonance (CMR) methods of assessing diastolic dysfunction remain a developing area. This study presents a novel CMR approach to quantification of diastolic dynamics, using 3D volume tracking of the mitral annulus (MA). The utility of this method is demonstrated by distinguishing diastolic MA excursion profiles between normal subjects and hypertrophic cardiomyopathy (HCM) patients. Results show that HCM hearts have slower relative MA sweep volume rates during early diastole, but higher MA sweep volume rates during atrial contraction. This technique offers further insight into ventricular filling biomechanics, and it incorporates information from both axial and longitudinal MA motions.

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